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Dr. NORMAN ENDE, M.D.

PROFESSOR OF PATHOLOGY AND LABORATORY MEDICINE
UMDNJ NEW JERSEY MEDICAL SCHOOL

 

Featured Articles
Studies Of The
Berashis Cell

Lymphangiosarcoma

The following case concerns a patient who had interscapulo thoracic amputation and various other modalities of therapy, including one unique approach.

Hematopoietic Transplantation

A series of eight transfusions consisting of 30 to 85 ml of umbilical cord blood was utilized to establish a hematopoietic transplant in a patient with acute lymphoblastic leukemia on conventional therapy.

Use of Human Umbilical Cord Blood for Stem Cell Transplantation
Chapter 17 in Levitt’s and Mertelsmann’s “Hematopoietic Stem Cells”

Chronological List Of Articles On Stem Cell Research And Related Studies 

The titles of studies and published articles by Dr. Norman Ende and his colleagues are listed below. Click on a title to  download a copy of the original article. You may also see an excerpt of the article by clicking where it says “See Excerpt”

Lymphangiosarcoma

Dr Milton Ende (brother of Dr. Norman Ende) describes a use of umbilical cord blood to try to inhibit the growth of a malignancy in a patient who had been diagnosed with lymphangiosarcoma. The procedure took place in 1963. According to the author this is the earliest recorded attempt to use fetal cord blood in therapy. Dr. Ende discusses the theory behind the procedure, including the possibility that something in infants’ blood prevented them from having malignancies.

1. Lymphangiosarcoma
See Excerpt



2. Hematopoietic Transplantation By Means Of Fetal Cord Blood
See Excerpt


3. Fetal Cord Blood’s Potential For Bone Marrow Transplant
See Excerpt


4. Spotlight On  Cord  Blood Transplant Reminds Them Of A VA Med First
See Excerpt


5. Production Of Human To Mouse Xenografts
See Excerpt


6. Correspondence Collection Of Umbilical Cord Blood 
See Excerpt


7. Murine Survival Of Lethal Irradiation With Use Of Human Umbilical Cord Blood
See Excerpt


8. The Lancet – History Of Umbilical Cord Blood Transplantation


9. Correspondence: Cord Blood Collection – Effects On Newborns


10. Effect Of Human Cord Blood On SJL/J Mice After Chemoablation And Irradiation


11. The Effect Of Human Cord Blood On SJL/J Mice


12.Questions To Be Answered About Umbilical Cord Blood


14. Use Of Human Umbilical Cord Blood For Stem Cell Transplantation


15. Auto-Immunity And Aids – A Commentary


16. Potential For Clinical Use Of Viable Pluripotent Progenitor Cells In Blood Bank Stored Human Umbilical Cord Blood


17. The Feasibility Of Using Blood Bank Stored Cord Blood – Unmatched For HLA – For Marrow Transplantation


18. Endogenous Hematopoiec Reconstitution Induced By Human Umbilical Cord Blood Cells In Immunocomprimised Mice-Implications For Adoptive Therapy


19. The Potential For The Use Of Mononuclear Cells From Human Umbilical Cord Blood In The Treatment Of Amyotrophic Lateral Sclerosis In SOD 1 Mice


20. The Berashis Cell – A Review – Is It Similar To The Embryonic Stem Cell
See Excerpt


21. Human Umbilical Cord Blood Effect On SOD Mice – Amyotrophic Lateral Sclerosis


22. Human Umbilical Cord Blood Cells Ameliorate Huntingtons Disease In Transgenic Mice


23. Human Umbilical Cord Blood Cells Ameliorate Alzheimers Disease In Transgenic Mice


24. Pooled Umbilical Cord Blood As A Possible Universal Donor For Marrow Reconstitution And Use In Nuclear Accidents


25. Commentary – Berashis Cells In Human Umbilical Cord Blood Vs Embryonic Stem Cells
See Excerpt


26. Parkinson’s Disease Mice And Human Umbilical Cord Blood


Download 27. NOD-LtJ Type 1 Diabetes In Mice And The Effect Of Stem Cells – Berashis – Derived From Human Umbilical Cord Blood
See Excerpt


28. Effect Of Human Cord Blood Mononuclear Cells On Preclinical Prostate Cancer Mice


29. Effect Of Human Umbilical Cord Blood Cells On Glycemia And Insulitis In Type 1 Diabetic Mice


30. Transplantation Of Human Umbilical Cord Blood Cells Improves Glycemia And Glomerular Hypertophy In Type 2 Diabetic Mice


31. The Effect Of Human Cord Blood Mononuclear Cells On Mouse Animal Model B6 V-Lepob Type 2 Diabetes


32. Administration Of Human Umbilical Cord Blood Cells Delays The Onset Of Prostate Cancer And Increases The Lifespan Of The Tramp Mouse


33. The Time Of Clamping The Umbilical Cord – A Controversial Aspect Of Stem Cell Research


34. Administration Of Human Umbilical Cord Blood To Low Birth Weight Infants May Prevent The Subsequent Development Of Type 2 Diabetes


35. Collection Of Fetal Blood For Stem Cell Research And Therapy


36. The Ende Brothers And The Arcane History Of The First Umbilical Cord Blood Hematapoietic Stem Cell Transplant


37. Prevention Of Atherosclerosis In LDL Receptor Mutant Mice By Human Umbilical Cord Blood Cells


38. Human Umbilical Cord Treatment Of United States Soldiers Following Neurological Injury


39. The Effect Of Human Umbilical Cord Blood Therapy On The Intestinal Tract Of Lethally Irradiated Mice


40. Administration Of Human Umbilical Cord Blood Cells Produces Interleukin 10 In IL-10 Deficient Mice


41. Use of Human Umbilical Cord Blood for Stem Cell Transplantation
Chapter 17 in Levitt’s and Mertelsmann’s “Hematopoietic Stem Cells”


42. Emergency Use Of Umbilical Cord Blood


Abstracts

Human Umbilical Cord Blood And Effect On SOD Mice


The Effect Of A Megadose Of Human Umbilical Cord Blood Mononuclear Cells On Huntington’s Disease Mice


The Effect Of A Megadose Of Human Umbilical Cord Blood Mononuclear Cells On Alzheimer’s Disease Mice


Effect Of Human Umbilical Cord Blood On Mice With Parkinson Disease


Human Umbilical Cord Blood Mononuclear Cells And Mice With Type 1 Diabetes


Delayed Onset Of Prostate Adenocarcinoma In Transgenic Mice By Use Of Human Umbilical Cord Blood


Effect Of Human Cord Blood Mononuclear Cells On Preclinical Prostate Cancer Mice Tramp


Human Umbilical Cord Blood Cell Administrations Reduction Of Atherosclerotic Plaques In The LDLR Mouse Without Immunosuppression


Effect Of Human Cord Blood Mononuclear Cells On Mouse Model B6 V-LEPOB Type 2 Diabetes