Lymphangiosarcoma

Lymphangioscarcoma

Report of a Case
Milton Ende, M.D.
Petersburg, Virginia

Dr Milton Ende (brother of Dr. Norman Ende) describes a use of umbilical cord blood to try to inhibit the growth of a malignancy in a patient who had been diagnosed with lymphangiosarcoma. The procedure took place in 1963. According to the author this is the earliest recorded attempt to use fetal cord blood in therapy. Dr. Ende discusses the theory behind the procedure, including the possibility that something in infants’ blood prevented them from having malignancies.

In 1948, Stewart and Treves described a new type of neoplasm beginning in edematous extremities following radical breast surgery. Since the initial case report, 75 patients have been described. Of this number, those having interscapulo thoracic amputation had the best results. Of 25 cases, 5 were living 1 to 11 years postoperative. Only 2 of 18 who had radiotherapy are alive; 1, 2 years after treatment, and 1, 12 years. All 13 who had wide excision and irradiation expired. Ten had amputation of the arm and of these 1 was alive 51 months following surgery. All 10 who had no specific treatment were dead within 1 year.

The following case concerns a patient who had interscapulo thoracic amputation and various other modalities of therapy, including one unique approach.

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Hematopoietic Transplantation by Means of Fetal Cord Blood