Spotlight On Cord Blood Transplant Reminds Them Of A VA Med First

Spotlight On Cord Blood Transplant
Reminds Them Of A VA Med First

Letters To The Editor – Virginia Medical Quarterly 1990;117:282

Considerable recent attention has been given to the use of umbilical cord blood for bone marrow transplantation by the medical literature as well as the lay press and television. This letter is written to address the fact that it was the Virginia Medical Monthly that published the original article on this usage in 1972 and raised the possibility of umbilical cord blood banks.

The clinical work was performed in Petersburg, VA, and the laboratory studies in Atlanta, GA. The article reported a patient with acute lymphoblastic leukemia who obtained a documented temporary graft following administration of a relatively small quantity of umbilical cord blood matched only for ABO typing.

Download Article Here

Fetal Cord Blood’s Potential For Bone Marrow Transplantation

Fetal Cord Blood’s Potential For
Bone Marrow Transplantation

Norman Ende, Pranela Rameshwar, Milton Ende

Department of Pathology and Medicine,
Division of Hematology,
University of Medicine and Dentistry Of New Jersey
New Jersey Medical School, Newark, NJ 07103

(Received in final form April 17, 1989)

Approximately 18 years ago, the authors were able to produce an apparently successful bone marrow transplant by using umbilical cord blood. In view of the Chernobyl disaster and the subsequent problems of treatment with marrow transplantation, this study undertook to explore further the potential use of umbilical cord blood as a source of marrow cells.

Specimens of umbilical cord blood were collected from 13 routine obstetrical deliveries. All specimens grew erythroid and granulocytic-monocytic colonies. The formation of these various hematopoietic colonies from umbilical cord blood was at least equivalent to bone marrow, and in some instances over 5 times more effective.

Download Article Here