Fetal Cord Blood’s Potential For Bone Marrow Transplantation

Fetal Cord Blood’s Potential For
Bone Marrow Transplantation

Norman Ende, Pranela Rameshwar, Milton Ende

Department of Pathology and Medicine,
Division of Hematology,
University of Medicine and Dentistry Of New Jersey
New Jersey Medical School, Newark, NJ 07103

(Received in final form April 17, 1989)

Approximately 18 years ago, the authors were able to produce an apparently successful bone marrow transplant by using umbilical cord blood. In view of the Chernobyl disaster and the subsequent problems of treatment with marrow transplantation, this study undertook to explore further the potential use of umbilical cord blood as a source of marrow cells.

Specimens of umbilical cord blood were collected from 13 routine obstetrical deliveries. All specimens grew erythroid and granulocytic-monocytic colonies. The formation of these various hematopoietic colonies from umbilical cord blood was at least equivalent to bone marrow, and in some instances over 5 times more effective.

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